Osteogenesis Imperfecta
Osteogenesis Imperfecta (OI), often known as "brittle bone disease," is a genetic disorder that affects the body’s ability to produce collagen, a key protein that helps strengthen bones. People with OI experience fragile bones that break easily, sometimes with little or no apparent cause. The severity of the condition can vary widely; some individuals may have only a few fractures in their lifetime, while others may suffer frequent breaks. OI can also cause other issues, such as dental problems and blue-tinted sclerae (the whites of the eyes). Management often involves physical therapy, medications, and in some cases, surgery.
Additional Insights
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Osteogenesis imperfecta (OI) is a genetic disorder that causes bones to break easily, often with little or no apparent cause. This condition arises from a defect in collagen, a protein that helps give bones their strength and structure. There are different types of OI, varying in severity, with some individuals experiencing frequent fractures, while others may have milder symptoms. Apart from bone fragility, OI can also affect teeth, hearing, and in some cases, growth. Treatment focuses on managing symptoms and preventing fractures, often involving physical therapy and, in severe cases, surgical interventions.