Sir A. E. Garrod

Sir Archibald Edward Garrod was a pioneering geneticist known for linking inherited traits to specific enzymes and metabolic disorders. He demonstrated that certain diseases, like alkaptonuria, are caused by genetic mutations affecting enzyme function, leading to the buildup of specific substances in the body. His work helped establish the field of inborn errors of metabolism, showing how genetics can influence biochemistry. Garrod's research laid the groundwork for modern medical genetics and personalized medicine, emphasizing the importance of understanding genetic variations in diagnosing and treating inherited conditions.