
Graft-versus-host disease
Graft-versus-host disease (GVHD) occurs when transplanted immune cells (graft) from a donor recognize the recipient's body as foreign and attack it. This often happens after bone marrow or stem cell transplants, where the donor's immune system may react against the recipient's tissues. Symptoms can include skin rashes, diarrhea, and liver problems. GVHD can be acute or chronic and may vary in severity. Managing GVHD involves balancing the body's immune response to protect against infections while preventing the donor cells from attacking the recipient's healthy tissues.
Additional Insights
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Graft Versus Host Disease (GVHD) is a condition that can occur after a stem cell or bone marrow transplant. It happens when the donated immune cells (the "graft") recognize the recipient's body (the "host") as foreign and attack it. This immune response can lead to various symptoms, including skin rashes, digestive issues, and liver problems. GVHD can be acute or chronic, varying in severity. While it can be a serious complication, doctors often monitor patients closely and may use medications to help manage the condition and reduce its impact on the recipient's health.