pathology of cardiac allograft vasculopathy

Cardiac allograft vasculopathy is a complication that can arise after a heart transplant. It involves the gradual narrowing of the blood vessels in the transplanted heart, similar to how arteries can clog with plaque in ordinary heart disease. This narrowing occurs due to the body's immune response reacting against the new heart, causing inflammation and thickening of the vessel walls. Over time, this can limit blood flow to the heart muscle, potentially leading to heart failure or other serious issues. Monitoring and managing this condition is crucial for the long-term health of transplant recipients.