histocompatibility

Histocompatibility refers to the compatibility of tissues from different individuals, particularly in the context of organ transplants. It involves specific proteins called human leukocyte antigens (HLAs) present on cell surfaces that help the immune system recognize what is self and what is foreign. If the donor's and recipient's HLAs match closely, the chances of transplant success increase, as the recipient's immune system is less likely to reject the new organ. Mismatched tissues can lead to complications, highlighting the importance of matching donors and recipients in medical procedures.