Rb (retinoblastoma protein)

Retinoblastoma protein (Rb) is a crucial tumor suppressor found in our cells. Its main role is to control cell growth and division by regulating the cell cycle, ensuring that cells do not grow uncontrollably. Rb acts like a gatekeeper, stopping cells from dividing when they shouldn’t, which helps prevent cancer. If Rb is malfunctioning or absent, cells can multiply excessively, increasing the risk of developing tumors, particularly in the eye, as seen in retinoblastoma, a rare childhood cancer. Understanding Rb is vital for cancer research and treatments.

Additional Insights

Retinoblastoma protein (Rb) is a crucial tumor suppressor protein in our cells. It helps control cell division and prevent excessive cell growth, which can lead to cancer. Rb works by regulating the cell cycle, specifically by hindering the progression of cells from a resting state to active division. When Rb is functioning properly, it can stop cells that are damaged or not ready to divide, thereby helping to maintain healthy tissue. Mutations in the Rb gene can lead to uncontrolled cell growth and are linked to various cancers, most notably retinoblastoma, a type of eye cancer seen in children.