E2F transcription factor

E2F transcription factors are a group of proteins that help control the process of cell division by turning certain genes on or off. They are essential for cell cycle progression, especially when a cell prepares to divide. E2F proteins are regulated by other molecules, such as the retinoblastoma protein (RB), which keeps them in check to prevent uncontrolled growth. Proper functioning of E2F ensures healthy cell replication, while their malfunction can lead to problems like cancer, as cells may divide excessively or uncontrollably.