PARP inhibitors
PARP inhibitors are a class of drugs used primarily in cancer treatment, particularly for cancers associated with genetic mutations like BRCA1 and BRCA2. They work by blocking an enzyme called PARP that helps repair DNA damage in cells. Cancer cells rely on this enzyme to fix their damaged DNA, so when PARP is inhibited, these cancer cells accumulate damage and can die, while healthy cells can often repair themselves. This targeted approach makes PARP inhibitors effective against certain types of tumors, offering a personalized treatment option for patients with specific genetic backgrounds.
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PARP inhibitors are a type of targeted cancer therapy that block the action of a protein called PARP, which helps repair damaged DNA in cells. Cancer cells often rely on PARP to survive and multiply when their DNA is damaged. By inhibiting this protein, PARP inhibitors make it harder for cancer cells to fix their DNA, leading to their death, while normal cells can usually repair themselves. These drugs are particularly effective in treating cancers linked to specific genetic mutations, such as breast and ovarian cancers. Researchers are continually studying their effectiveness across various types of cancer.