Janus Kinases (JAK)

Janus kinases (JAK) are a type of enzyme found in cells that play a crucial role in how our body responds to signals from various hormones and immune system molecules. They help transmit messages from the outside of a cell to its interior, which influences processes like inflammation, immune response, and blood cell production. When the JAK pathway is not functioning correctly, it can lead to diseases such as arthritis, certain cancers, and autoimmune disorders. Medications that inhibit JAK can help treat these conditions by blocking the overactive signals that cause inflammation or other issues.