JAK/STAT pathway

The JAK/STAT pathway is a vital signaling mechanism in cells that helps them respond to various signals, such as hormones and growth factors. It involves two key components: JAK (Janus kinase), an enzyme, and STAT (signal transducer and activator of transcription), a protein. When a signaling molecule binds to a surface receptor on a cell, JAK activates and then triggers STAT. Activated STAT moves into the cell nucleus and affects gene expression, influencing processes like immunity, cell division, and inflammation. This pathway plays a crucial role in maintaining health and regulating responses to signals in the body.