3D Genome Structure

The 3D genome structure refers to the spatial arrangement of DNA within a cell's nucleus. Instead of being a long, tangled thread, DNA is organized into specific shapes and regions that bring distant genes closer together. This organization influences how genes are expressed and regulated. Think of it like a library, where books (genes) are arranged on shelves (chromosomes) in a way that makes it easier for librarians (cell machinery) to find and read them. Understanding this structure helps scientists learn how genes interact and how disruptions can lead to diseases.