Structural Variation

Structural variation refers to differences in the structure of genetic material among individuals in a population. This can include deletions, duplications, inversions, or rearrangements of DNA segments. Unlike single-point mutations, which affect only one base pair, structural variations can impact larger sections of chromosomes and influence gene function or regulation. They play a significant role in genetic diversity, evolution, and can be associated with various diseases. Understanding structural variation helps researchers uncover the complexities of genetics and its implications for health and disease.