TP53 gene

The TP53 gene provides instructions for making a protein called p53, which plays a crucial role in regulating the cell cycle and preventing tumor formation. Often referred to as the "guardian of the genome," p53 helps detect DNA damage and can trigger repair processes or lead to cell death if the damage is irreparable. Mutations in the TP53 gene are commonly found in various cancers, impairing its protective functions and allowing cells to grow uncontrollably. Understanding TP53 is vital in cancer research, as restoring its function may offer new therapeutic strategies.