TP53

TP53 is a gene that provides instructions for making a protein called p53, which plays a critical role in protecting cells from becoming cancerous. Often referred to as the "guardian of the genome," p53 helps repair DNA damage, regulate the cell cycle, and trigger cell death if the damage is too severe. When the TP53 gene is mutated, its ability to control these processes is impaired, leading to uncontrolled cell growth and the development of tumors. Mutations in TP53 are common in many types of cancer, making it a key focus of cancer research and treatment strategies.