TP53 mutations

TP53 is a gene that produces a protein crucial for regulating cell growth and preventing tumor formation. When mutations occur in the TP53 gene, it can lead to dysfunction of the protein, allowing abnormal cells to divide uncontrollably. This is commonly associated with many types of cancer, as the body loses an important safeguard against tumor development. TP53 mutations are found in a variety of cancers, including breast, lung, and colon cancer, and understanding these mutations helps in cancer research and developing targeted therapies.