Coagulation Cascade
The coagulation cascade is a series of complex chemical reactions in the body that occur when a blood vessel is injured. It involves proteins in the blood, called clotting factors, that work in a specific sequence to form a stable blood clot. This process helps stop bleeding (hemostasis) and is vital for healing. However, if the cascade becomes overactive, it can lead to unwanted blood clots (thrombosis), which can block blood flow and cause serious health issues. Understanding this balance is crucial for maintaining proper blood flow and preventing complications.
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The coagulation cascade is a complex series of biochemical reactions in the body that helps stop bleeding when we get injured. When a blood vessel is damaged, proteins in the blood activate one another in a precise sequence. This cascade leads to the formation of fibrin, which creates a mesh that solidifies the blood, forming a clot. The process involves both intrinsic pathways (activated by damage to the vessel) and extrinsic pathways (triggered by tissue injury). Together, these pathways ensure that blood loss is minimized, allowing the body to heal effectively.