Caloric Restriction Mimetics

Caloric Restriction Mimetics (CRMs) are substances that can mimic the effects of reducing calorie intake without actually decreasing food consumption. Research suggests that calorie restriction can lead to health benefits, such as increased lifespan and improved metabolic health. CRMs may activate similar biological pathways that calorie restriction does, potentially promoting longevity and reducing age-related diseases. Common examples include certain compounds found in plants, like resveratrol, and drugs like metformin. By influencing these processes, CRMs hold promise for enhancing health and longevity without requiring significant dietary changes.