ASXL1

ASXL1 is a gene that provides instructions for making a protein involved in regulating gene expression and maintaining normal cell function. Mutations in the ASXL1 gene can lead to problems with blood cell production and are associated with various types of blood cancers, such as acute myeloid leukemia and myelodysplastic syndromes. When ASXL1 is altered, it can disrupt normal cellular processes, leading to uncontrolled cell growth and the development of cancer. Researchers study ASXL1 to understand its role in these conditions and to seek potential therapies that target the effects of its mutations.