NPM1 Mutation

NPM1 mutation involves changes in a gene called NPM1, which plays a role in cell growth and division. When this gene mutates, it can cause abnormal blood cell development, often seen in a type of blood cancer called acute myeloid leukemia (AML). This mutation leads to the production of defective proteins that disrupt normal blood cell functions and can influence how the disease progresses and responds to treatment. Detecting NPM1 mutations helps doctors better understand the disease and tailor treatment options for affected patients.