ASXL1 Mutation

ASXL1 mutation involves changes in the ASXL1 gene, which plays a role in regulating gene activity and bone marrow function. These mutations are often found in blood cancers such as myelodysplastic syndromes and acute myeloid leukemia. When mutated, ASXL1 may disrupt normal blood cell development, leading to abnormal cell growth and impaired blood formation. Detecting this mutation can help diagnose, predict disease progression, and guide treatment decisions in affected patients.