Antibody-Mediated Rejection
Antibody-mediated rejection is a process that occurs when the body’s immune system identifies a transplanted organ, like a kidney or heart, as foreign. In this case, antibodies—proteins produced by the immune system—attack the new organ. This can happen if the donor's tissues have different markers than the recipient’s, leading to inflammation and damage. Symptoms may include pain or dysfunction of the transplanted organ. To prevent or treat this rejection, doctors may use medications that suppress the immune response, helping to ensure the transplanted organ functions effectively.
Additional Insights
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Antibody-mediated rejection occurs when the immune system mistakenly identifies transplanted tissue or organs as foreign and attacks them. This happens when the body produces antibodies, which are proteins designed to fight off infections, against the donor's cells. If these antibodies bind to the donor's blood vessels, it can lead to inflammation and damage, ultimately jeopardizing the transplanted organ. This type of rejection often happens more quickly than other forms, making it crucial for transplant recipients to take medications to suppress their immune response and prevent these harmful reactions.