Ubiquitination-related diseases

Ubiquitination is a cellular process where a small protein called ubiquitin attaches to other proteins, marking them for destruction or altering their function. When this process goes awry, it can lead to various diseases. For example, improper ubiquitination is linked to cancer, neurodegenerative disorders like Alzheimer's and Parkinson's, and immune system problems. Essentially, when cells can't properly manage proteins through ubiquitination, it disrupts normal cellular functions, contributing to disease development. Understanding these mechanisms is crucial for developing targeted therapies and improving health outcomes.