NF-kB (Nuclear Factor kappa-light-chain-enhancer of activated B cells)

NF-κB is a protein complex that acts as a key regulator in the body's immune response and inflammation. It functions as a control switch inside cells, activating genes involved in fighting infections, promoting cell survival, and managing inflammation. When the body detects danger, NF-κB moves into the cell nucleus and turns on specific genes. While crucial for defending the body, excessive or uncontrolled NF-κB activity can contribute to chronic inflammation and diseases like cancer. Understanding NF-κB helps researchers develop treatments for conditions linked to immune system dysfunction and inflammation.