TRAF (TNF Receptor-Associated Factor)

TRAF (TNF Receptor-Associated Factor) refers to a family of proteins that play a crucial role in the immune system. They help transmit signals from receptors on cell surfaces into the cells, influencing how cells respond to inflammation, infection, or stress. TRAF proteins work with tumor necrosis factor (TNF) receptors, which are involved in regulating immune responses and cell survival. Essentially, TRAFs are key players in helping the body manage its defenses, making them important for both health and disease, including autoimmune disorders and cancers.