NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells)

NF-κB, or nuclear factor kappa-light-chain-enhancer of activated B cells, is a protein complex that plays a crucial role in regulating the immune response and inflammation in our bodies. When cells are activated by stress, infection, or other stimuli, NF-κB moves into the nucleus and turns on genes that help fight off infections and promote cell survival. However, if NF-κB is overly active or deregulated, it can contribute to chronic inflammation and diseases like cancer, autoimmune disorders, and neurodegenerative conditions, making it an important focus for research and potential therapies.