Structure-Activity Relationship (SAR)

Structure-Activity Relationship (SAR) is the study of how the chemical structure of a molecule affects its biological activity. By analyzing the relationship between the molecular structure (like shape, size, and functional groups) and how well the molecule works in a particular biological context (like interacting with a target in the body), scientists can identify key features that influence effectiveness. This knowledge helps in designing new compounds, such as drugs, that have desired effects while minimizing side effects, ultimately leading to the development of better treatments and pharmaceuticals.