ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity)

ADMET stands for Absorption, Distribution, Metabolism, Excretion, and Toxicity—key factors in determining how a drug behaves in the body. Absorption is how the drug enters the bloodstream; Distribution refers to how it spreads throughout the body; Metabolism involves the body's process of breaking down the drug; Excretion is how the body eliminates it; and Toxicity assesses potential harmful effects. Understanding ADMET helps scientists predict a drug’s effectiveness and safety, ensuring it works properly without causing undue harm, and guides the development of better, safer medications.