Myeloid-derived suppressor cells

Myeloid-derived suppressor cells (MDSCs) are a type of immune cell that play a role in regulating the body's immune responses. They can inhibit the activity of other immune cells, which is important in preventing excessive reactions to pathogens or tissues but can also allow cancer cells to grow unchecked. MDSCs are often increased in cancer and chronic infections, where they help the body avoid overwhelming inflammation. While they serve a protective function, their presence can complicate treatments like immunotherapy by dampening the immune system’s ability to attack tumors effectively.