MDSC (Myeloid-derived suppressor cells)

Myeloid-derived suppressor cells (MDSCs) are a group of immune cells that normally help regulate the immune response. However, in certain conditions like cancer or chronic infections, they become overactive and suppress the body's ability to fight disease. They do this by inhibiting other immune cells that attack tumors or infected cells, effectively helping the disease evade the immune system. Understanding MDSCs is important because they influence disease progression and can be targeted in therapies to improve immune responses against cancer and other illnesses.