MEFV gene

The MEFV gene provides instructions for producing a protein called pyrin, which plays a crucial role in regulating the body's immune response. Mutations in this gene are linked to Familial Mediterranean Fever (FMF), a hereditary condition that causes recurrent fevers and inflammation in various body parts, particularly affecting people of Mediterranean descent. Individuals with FMF often experience episodes of pain and swelling, which can be managed with medication. Understanding MEFV helps in diagnosing and treating FMF, highlighting the importance of genetics in health and disease.