Familial Mediterranean Fever (FMF)

Familial Mediterranean Fever (FMF) is a genetic condition that causes recurring episodes of fever and inflammation, often in the abdomen, chest, or joints. It primarily affects people of Mediterranean descent, including those with Armenian, Arab, or Jewish ancestry. The disease is linked to mutations in the MEFV gene, which helps regulate the body's immune response. Symptoms typically appear in childhood or early adulthood, and crises usually last one to three days. FMF can lead to complications like kidney damage if untreated. Regular use of colchicine, a medication, can help manage symptoms and prevent flare-ups.