autoinflammatory syndromes

Autoinflammatory syndromes are conditions where the immune system mistakenly triggers inflammation without an external infection or injury. In these syndromes, certain immune pathways become overactive, causing episodes of persistent or recurring inflammation, pain, fever, and other symptoms. They are often inherited or related to genetic mutations, leading to abnormal immune responses. Unlike autoimmune diseases that involve antibodies attacking the body's own tissues, autoinflammatory syndromes mainly involve innate immune cells that release inflammatory chemicals. Proper diagnosis and treatment can manage symptoms and reduce inflammation, improving quality of life for affected individuals.