CTLA-4

CTLA-4, or Cytotoxic T-Lymphocyte Antigen 4, is a protein found on the surface of T cells, which are key players in the immune system. It acts as a brake, regulating the immune response to prevent it from becoming too aggressive and harming the body’s own tissues. By binding to specific molecules on other immune cells, CTLA-4 helps maintain balance in the immune system, ensuring it responds effectively to threats like infections and cancer while avoiding damage to healthy cells. Understanding CTLA-4 is crucial in immunotherapy, where its blockade can enhance the body's fight against tumors.