ChIP-Seq

ChIP-seq, or Chromatin Immunoprecipitation Sequencing, is a technique used to study how proteins interact with DNA in cells. It involves cross-linking proteins to DNA, then using antibodies to isolate specific proteins, and finally sequencing the associated DNA. This allows researchers to identify the locations where proteins, such as transcription factors, bind to the genome. Understanding these interactions helps illuminate the regulatory mechanisms of gene expression and their roles in various biological processes and diseases.