Chromatin Immunoprecipitation (ChIP)

Chromatin Immunoprecipitation (ChIP) is a laboratory technique used to study how proteins interact with DNA in cells. It allows researchers to identify specific proteins that bind to particular DNA regions, which is important for understanding gene regulation. The process involves cross-linking proteins to DNA, then using antibodies to isolate the protein-DNA complexes. After separating them, scientists can analyze the DNA to see which genes are affected by those proteins. This technique provides insights into processes like cell development, disease mechanisms, and how genes are turned on or off in different conditions.