Androgen Insensitivity Syndrome
Androgen Insensitivity Syndrome (AIS) is a genetic condition where a person with XY chromosomes (typically male) is unable to respond to male hormones called androgens. This means that despite having male genes, their body may develop female physical traits or remain ambiguous. Individuals with AIS may be raised as girls and might not realize they have a male genetic background until later in life, often during puberty when they don't start menstruating. AIS varies in severity, with some experiencing complete insensitivity (CAIS) and others partial (PAIS). It highlights the complex interplay between genetics, hormones, and physical development.
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Androgen Insensitivity Syndrome (AIS) is a genetic condition where a person is genetically male (with XY chromosomes) but their body does not respond to male hormones called androgens. As a result, individuals with AIS may develop typical female physical characteristics, such as breasts and a female body shape, although they may have undescended testes and no uterus. AIS can be complete (where there’s no response to androgens) or partial (where there’s some response). People with this condition often identify as female and may not discover their condition until puberty or adulthood.