
Ames test
The Ames test is a laboratory procedure used to assess whether a substance might cause mutations in DNA and potentially lead to cancer. It involves exposing special strains of bacteria to the substance in question. If the bacteria show an increase in mutations, it suggests the substance could be harmful. Researchers use this test as an early screening method to determine the safety of chemicals, drugs, and food additives before further testing in more complex organisms. It’s named after Dr. Bruce Ames, who developed the test in the 1970s.
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The Ames Test is a laboratory experiment used to assess whether a substance can cause genetic mutations, which are often linked to cancer. It involves exposing harmless bacteria to the chemical in question and observing if the bacteria mutate and grow in a way they normally wouldn't. If the chemical induces mutations, it may be considered a potential carcinogen. This test is important in assessing the safety of new chemicals, drugs, and food additives, helping researchers understand the potential risks they may pose to human health.