Ubiquitin-conjugating enzymes (E2)

Ubiquitin-conjugating enzymes, known as E2 enzymes, play a critical role in protein regulation within cells. They are responsible for attaching a small protein called ubiquitin to other proteins. This process, known as ubiquitination, marks proteins for various fates, such as degradation or altering their activity. E2 enzymes act as intermediaries, transferring ubiquitin from a donor molecule to the target protein, ensuring that cellular processes function smoothly. By managing protein levels and functions, E2 enzymes are vital for maintaining overall cellular health and responding to stress or damage.