E2 enzyme family

The E2 enzyme family are specialized proteins that play a crucial role in the process of attaching a small molecule called ubiquitin to other proteins within cells. This tagging process, called ubiquitination, helps regulate protein functions, mark proteins for degradation, or alter their activity. E2 enzymes work by accepting ubiquitin from an E1 activating enzyme and then transferring it to a target protein, often with the assistance of an E3 ligase. There are many types of E2 enzymes, each with specific roles, ensuring precise control over protein life cycles and cellular functions.