Tumor Mutational Burden

Tumor Mutational Burden (TMB) refers to the total number of genetic mutations found in a tumor's DNA. Higher TMB can indicate more mutations, which may help the immune system recognize and attack cancer cells. It is important in cancer treatment, as patients with high TMB might respond better to certain immunotherapies that boost the immune response. Doctors measure TMB to help personalize treatment plans and predict a patient's prognosis, making it a significant factor in cancer research and therapy development. Understanding TMB can lead to more effective and targeted cancer treatments.