Spindle Assembly Checkpoint

The spindle assembly checkpoint (SAC) is a critical control mechanism during cell division. It ensures that chromosomes are properly aligned and attached to the spindle fibers before a cell divides. If there are any issues, the checkpoint halts the process, preventing errors like uneven distribution of genetic material. This safeguard helps maintain genetic stability and prevents conditions such as cancer. Essentially, the SAC acts like a quality control system, ensuring that everything is ready for the cell to split safely and correctly.