Protein aggregation theory

Protein aggregation theory refers to the process where proteins, which are essential for various biological functions, misfold and clump together. This can lead to the formation of larger structures that are often nonfunctional or toxic to cells. Such aggregates are implicated in several diseases, including Alzheimer's and Parkinson's. Essentially, when proteins do not achieve their correct shape due to genetic mutations or environmental factors, they can lose their normal functions and cause harmful effects in the body, highlighting the importance of proper protein folding for health.