
Notch signaling
Notch signaling is a communication system between cells that helps regulate their development and function. It involves a receptor called Notch on a cell's surface, which interacts with specific proteins (ligands) on neighboring cells. When the ligand binds to Notch, it triggers a change inside the cell, influencing gene activity. This process is crucial for proper cell growth, differentiation, and tissue formation during development and in adult tissues. Notch signaling maintains the balance between cell renewal and specialization, and errors in this pathway can lead to diseases such as cancer.