Mitochondrial DNA (mtDNA) mutations

Mitochondrial DNA (mtDNA) mutations are changes that occur in the genetic material found in mitochondria, the energy-producing structures in our cells. Unlike the DNA in the nucleus, mtDNA is inherited only from the mother. These mutations can affect how well mitochondria function, potentially leading to various health issues, especially in energy-demanding organs like the brain and muscles. While some mutations may have little to no impact, others can contribute to diseases or metabolic disorders. Researchers study mtDNA mutations to better understand their role in health and disease, as well as their potential implications in aging.