Ionizable lipids

Ionizable lipids are a type of lipid molecule that can change their electrical charge depending on the pH of their environment. This property allows them to interact effectively with biological membranes and facilitate the delivery of genetic material into cells, particularly in the context of mRNA vaccines. By switching between charged and neutral states, they can form tiny particles that encapsulate the genetic material, making it easier for the body to take these molecules up. Their unique behavior is crucial for enhancing the effectiveness of various therapeutic strategies, especially in gene therapy and vaccination.