Histone deacetylases (HDACs)
Histone Deacetylases (HDACs) are enzymes that play a crucial role in regulating gene expression. They remove acetyl groups from proteins called histones, which help package DNA in our cells. This removal can lead to tighter DNA packing, making it less accessible for gene activation. Consequently, HDACs can silence or reduce the expression of certain genes. They are important in many biological processes, including cell growth and differentiation, and are being studied for their potential roles in cancer and other diseases, where abnormal gene expression occurs.
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Histone deacetylases (HDACs) are enzymes that play a crucial role in regulating gene expression. They modify histones, which are proteins that help package DNA in our cells. By removing acetyl groups from histones, HDACs make the DNA more tightly wrapped, reducing the accessibility of genes for reading. This can lead to decreased gene activity. HDACs are important in various cellular processes, including cell growth, differentiation, and response to stress. Because they influence gene expression, they are also studied for their roles in diseases like cancer and for potential therapeutic applications.