HDAC inhibitors

HDAC inhibitors are a class of drugs that block the activity of enzymes called histone deacetylases (HDACs). These enzymes help regulate gene expression by modifying how tightly DNA is wound around proteins called histones. When HDACs are inhibited, the DNA remains more open and accessible, allowing for increased expression of certain genes. This can influence processes like cell growth, differentiation, and death, making HDAC inhibitors valuable in treating some cancers and diseases involving abnormal gene activity. They essentially help modulate gene function by altering the epigenetic landscape of cells.