Vorinostat (SAHA)

Vorinostat, also known as SAHA, is a medication that helps treat certain types of cancer, such as cutaneous T-cell lymphoma. It works by blocking enzymes called histone deacetylases (HDACs), which normally remove acetyl groups from proteins that package DNA. By inhibiting these enzymes, vorinostat changes how genes are turned on or off, leading to the cancer cells stopping their growth, dividing less, or dying. This targeted approach can help slow or stop the progression of cancer, making vorinostat a valuable option in cancer therapy.