ATP-competitive inhibitors

ATP-competitive inhibitors are a type of drug that block the activity of enzymes by binding to the same site where ATP (adenosine triphosphate), the cell's energy currency, would normally attach. By occupying this site, these inhibitors prevent ATP from binding, which inhibits the enzyme's function. This can be useful in treating diseases, particularly cancers, where enzymes are overly active. Essentially, they disrupt the enzyme's ability to perform its job, slowing down or stopping processes that help cancer cells grow and survive.