ABL1 (Abl Tyrosine Kinase)

ABL1, also known as Abl Tyrosine Kinase, is a gene that produces a protein functioning as an enzyme involved in cell signaling, growth, and division. It plays a crucial role in normal cell processes by transferring a phosphate group to other proteins, which helps regulate their activity. When ABL1 is functioning properly, it supports healthy cell behavior. However, mutations can cause it to become overactive, leading to uncontrolled cell growth, as seen in some cancers like chronic myeloid leukemia (CML). Medications targeting ABL1 are used to treat such conditions by inhibiting its abnormal activity.